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MYP_167320
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Basic Information
Lf-CATH1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
30 amino acids
C139H233N43O38S2
Standard
Sequence
PPCRGIFCRRVGSSSAIARPGKTLSTFITV
Physicochemical Analysis
3178.73 Da
11.54
4.94
4.85
0.1646
0.22
0.60
0.03
44.72
78.00
0.0667
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1290.88
-16.04
51.0
45.0
100.0
222.0
5.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0123580 VERIFIED: YES
Provenance & Taxonomy
Limnonectes fragilis [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-8
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans ATCC 2002
1.26 μM
MIC
PaperIdentification and polymorphism discovery of the cathelicidins, Lf-CATHs in ranid amphibian (Limnonectes fragilis).
RECORD: Rec_0127213 VERIFIED: YES
Provenance & Taxonomy
Limnonectes fragilis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 27853
10.1 μM
MIC
PMID24028327 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24028327/
RECORD: Rec_0127943 VERIFIED: YES
Provenance & Taxonomy
Limnonectes fragilis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 2592
1.26 μM
MIC
PMID24028327 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24028327/
RECORD: Rec_0169596 VERIFIED: YES
Provenance & Taxonomy
Limnonectes fragilis [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-8
Bio-Activity Profile
Antimicrobial Antifungal
Gram-positive Staphylococcus aureus ATCC 2592 or IS 1303 or IS 1349
1.25-10 μM
MIC
PaperIdentification and polymorphism discovery of the cathelicidins, Lf-CATHs in ranid amphibian (Limnonectes fragilis).
RECORD: Rec_0199098 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 13.3%, T 43.3%, C 43.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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