Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length229 amino acids

Chemical FormulaC1174H1778N270O353S9

DescriptionStandard

        PVRIDDLAEIDYSLNSLEVFQPYIDMDLKGIVYPAGNHTGPSYVAAPFAIPDQSDYMFYFAVSEYFFQTYVFSYYTTGAFNITIAETCRYFNISTEMFGSLIPEVAKYSIIPNPVMMKLMPTEIPLISFQKNSFTLEIEESMEVFAVLPDSTTQPLFTVNVAANTSIDLNVFDQKLTGSLCLNRLQFSLAHSDVGSFEISLVENILSYILQTEVIPSVNGKATTPSHTV
    

Molecular Weight25610.86 Da

Isoelectric Point (pI)4.25

Net Charge (pH 7.0)-15.77

Net Charge (pH 7.4) -16.06

Charge Density (pH 7.0) -0.0689

GRAVY Index0.20

Hydrophobic Moment 0.54

Boman Index0.22

Instability Index41.54

Aliphatic Index 93.62

Aromaticity 0.1310

Extinction Coeff. Reduced 19370.00

Extinction Coeff. Oxidized 19495.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0214514 VERIFIED: NO

Provenance & Taxonomy

OrganismOdontophorus gujanensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria