Peptide Database

Peptide NameHepcidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC432H678N118O125S13

DescriptionStandard

        MKAFSIAVAVTLVLAFIFIEESSAVPFTGVGELEEAGGNDTPVEAHQEMSMESWMMPKHVREKRQSHLSLCRYCCKCCKNKGCGFCCRF
    

Molecular Weight9941.57 Da

Isoelectric Point (pI)6.80

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.81

Charge Density (pH 7.0) -0.0033

GRAVY Index0.04

Hydrophobic Moment 0.63

Boman Index0.06

Instability Index55.21

Aliphatic Index 65.73

Aromaticity 0.0899

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3871.19

LogP -36.85

H-bond Donors 142.0

H-bond Acceptors 141.0

Rotatable Bonds 331.0

Heavy Atoms 688.0

Ring Count 15.0

Amide Bonds 92.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0318566 VERIFIED: NO

Provenance & Taxonomy

OrganismFundulus heteroclitus [Bacterium]

FamilyHepcidin

Tax ID8078

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal