Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length225 amino acids

Chemical FormulaC1151H1758N258O339S10

DescriptionStandard

        LCIHKIISMFFVIFCVLSTTLRAVMQIDDLAEVVYSLSGLPAVFQTFIDLDLKGVVFPAGNHTDSPYMAASFTIPDQSDSMLYLAFSEYFFQSSSFAYYTTGAFNMTIAEEVKSGNSFVFSLLFFPSDLSYFKINTEIFSSTIPEVAKYSITPYLVIFKLMSSEIPTISLQQDSFTAEIQGSVEVLAILPDSTTQSLFTLTIAANTSISLNIFDQKLMGSLCLNR
    

Molecular Weight24954.44 Da

Isoelectric Point (pI)4.33

Net Charge (pH 7.0)-11.07

Net Charge (pH 7.4) -11.47

Charge Density (pH 7.0) -0.0492

GRAVY Index0.51

Hydrophobic Moment 0.61

Boman Index0.28

Instability Index44.12

Aliphatic Index 100.98

Aromaticity 0.1378

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0326954 VERIFIED: NO

Provenance & Taxonomy

OrganismMolothrus ater [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria