Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length102 amino acids

Chemical FormulaC537H868N154O147S7

DescriptionStandard

        MRLFLIVAILLFQKPTETEQLKKCWGHYIQGNCRKVCRVTEIREVLCENRRYCCLNIKQLEERKKVTVRPRPKPPTFAATFPPYKDVEITPSSGSQDRQYIN
    

Molecular Weight12058.04 Da

Isoelectric Point (pI)9.54

Net Charge (pH 7.0)8.54

Net Charge (pH 7.4) 8.15

Charge Density (pH 7.0) 0.0837

GRAVY Index-0.55

Hydrophobic Moment 0.69

Boman Index-0.17

Instability Index55.24

Aliphatic Index 80.20

Aromaticity 0.0882

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4916.87

LogP -43.17

H-bond Donors 176.0

H-bond Acceptors 164.0

Rotatable Bonds 401.0

Heavy Atoms 845.0

Ring Count 19.0

Amide Bonds 111.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0419305 VERIFIED: NO

Provenance & Taxonomy

OrganismSpermophilus dauricus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence