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MYP_167259
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Basic Information
Beta-lactorphin
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Metabolic ▸ Uric acid metabolism ▸ Hypouricemic activity
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid receptor ligand
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Regulatory peptide ▸ Stimulation activity
Sensory / Food function ▸ Taste-active peptide
Sensory / Food function ▸ Taste-active peptide ▸ Bitter peptide
Standard
4 amino acids
C26H34N4O6
Standard
Sequence
YGLF
Physicochemical Analysis
498.57 Da
5.52
-0.24
-0.45
-0.0602
1.23
0.24
0.75
-13.72
97.50
0.5000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
170.85
0.72
6.0
6.0
13.0
36.0
2.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0266215 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
733 μM
IC50
PaperAntihypertensive peptides: production, bioavailability and incorporation into foods. PMID21185549 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21185549/
RECORD: Rec_0302833 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperMilk peptides and blood pressure. PMID17311982 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17311982/
RECORD: Rec_0325614 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
ACE-inhibitory peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperBioactive peptides derived from milk proteins and their health beneficial potentials: an update. PMID21773582 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21773582/
RECORD: Rec_0364288 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
PaperAmigo L., Mart¨ªnez-Maqueda D., Hern¨¢ndez-Ledesma B.. In silico and in vitro analysis of multifunctionality of animal food-derived peptides. Foods, 9, 991, 2020.
RECORD: Rec_0382139 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-Lactalbumin-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant Macrophage-modulating
Caco-2 cells
PaperIn Silico and In Vitro Analysis of Multifunctionality of Animal Food-Derived Peptides | Amigo, L. et al. | DOI: 10.3390/foods9080991 Evidence URLhttps://www.uniprot.org/uniprotkb/P00711/entry
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