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MYP_167259
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Basic Information
Beta-lactorphin
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Metabolic ▸ Uric acid metabolism ▸ Hypouricemic activity
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid receptor ligand
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Regulatory peptide ▸ Stimulation activity
Sensory / Food function ▸ Taste-active peptide
Sensory / Food function ▸ Taste-active peptide ▸ Bitter peptide
Standard
4 amino acids
C26H34N4O6
Standard
Sequence
YGLF
Physicochemical Analysis
498.57 Da
5.52
-0.24
-0.45
-0.0602
1.23
0.24
0.75
-13.72
97.50
0.5000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
170.85
0.72
6.0
6.0
13.0
36.0
2.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0198456 VERIFIED: NO
Provenance & Taxonomy
Salvia hispanica [Plant]
ACE-inhibitory peptide
4116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
Spontaneously hypertensive rat (SHR); Wistar-Kyoto rat (WKY)
23.4 mmHg
SBP decrease
PaperWhey Proteins as Source of Bioactive Peptides Against Hypertension
RECORD: Rec_0208575 VERIFIED: NO
Provenance & Taxonomy
Salvia hispanica [Plant]
ACE-inhibitory peptide
4116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
733 μM
IC50
PaperWhey Proteins as Source of Bioactive Peptides Against Hypertension
RECORD: Rec_0231654 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Stimulatory
PaperMart¨ªnez-Maqueda D., Miralles B., De Pascual-Teresa S., Rever¨®n I., Mu?oz R., Recio I.. Food-derived peptides stimulate mucin secretion and gene expression in intestinal cells. J. Agric. Food Chem., 60, 8600-8605, 2012.
RECORD: Rec_0237728 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Agonist
opioid receptor
300.0
PaperChiba H., Yoshikawa M.. Biologically functional peptides from food proteins: new opioid peptides from milk proteins. In Protein Tailoring for Food and Medical Uses, eds R. E. Feeney and J. R. Whitaker. Marcel Dekker, New York, pp. 123-153, 1986.
RECORD: Rec_0241454 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
Spontaneously hypertensive rat (SHR)
23.4 mmHg
SBP decrease
PaperAntihypertensive peptides from food proteins: a review. PMID22249830 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22249830/
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