Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC559H898N150O163S3

DescriptionStandard

        PDLSGYEKFGLGNVKYNISRIRVIAVEFPSASISLIPGAGIKLVIGNVSLTIDMNWNIRTWMFKDTGRSTVYISKVFVTAVFSTPVDNRGHTLISLTSCRTASGDIDIKLNGKS
    

Molecular Weight12424.21 Da

Isoelectric Point (pI)9.67

Net Charge (pH 7.0)5.04

Net Charge (pH 7.4) 4.89

Charge Density (pH 7.0) 0.0442

GRAVY Index0.15

Hydrophobic Moment 0.53

Boman Index0.13

Instability Index13.17

Aliphatic Index 101.67

Aromaticity 0.0877

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5030.84

LogP -51.51

H-bond Donors 181.0

H-bond Acceptors 172.0

Rotatable Bonds 411.0

Heavy Atoms 875.0

Ring Count 17.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0211721 VERIFIED: NO

Provenance & Taxonomy

OrganismDromaius novaehollandiae [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria