Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC482H788N122O135S8

DescriptionStandard

        MKLFLVLIILLFEVPTDAVRPKKCFNNIAGYCRKKCEMGEISEISCLNGKLCCVNEGRNKKQEEAKDVLQFPLLSDQKLDYVILPTITVFTIQP
    

Molecular Weight10708.67 Da

Isoelectric Point (pI)8.22

Net Charge (pH 7.0)1.45

Net Charge (pH 7.4) 1.12

Charge Density (pH 7.0) 0.0155

GRAVY Index0.10

Hydrophobic Moment 0.58

Boman Index0.06

Instability Index47.39

Aliphatic Index 107.77

Aromaticity 0.0745

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4151.75

LogP -30.72

H-bond Donors 144.0

H-bond Acceptors 145.0

Rotatable Bonds 365.0

Heavy Atoms 747.0

Ring Count 12.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0170518 VERIFIED: NO

Provenance & Taxonomy

OrganismPteropus alecto [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0353559 VERIFIED: NO

Provenance & Taxonomy

OrganismPteropus vampyrus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin