Peptide Database

Peptide NameSLAY-screened peptide P3879

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC90H148N32O28S

DescriptionStandard

        ASRTHLHATTPCLDTGIAHR
    

Molecular Weight2158.40 Da

Isoelectric Point (pI)8.32

Net Charge (pH 7.0)1.05

Net Charge (pH 7.4) 0.69

Charge Density (pH 7.0) 0.0524

GRAVY Index-0.39

Hydrophobic Moment 0.27

Boman Index-0.06

Instability Index4.74

Aliphatic Index 73.50

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 955.72

LogP -12.71

H-bond Donors 36.0

H-bond Acceptors 33.0

Rotatable Bonds 66.0

Heavy Atoms 151.0

Ring Count 4.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0404610 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/