Peptide Database

Peptide NameBeta-defensin 1TB

Function Ontology

—

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC161H249N47O47S7

DescriptionStandard

        DHYMCARKGGTCNFSPCPLFTRLEGTCYGGKAKCC
    

Molecular Weight3819.44 Da

Isoelectric Point (pI)8.65

Net Charge (pH 7.0)2.79

Net Charge (pH 7.4) 2.44

Charge Density (pH 7.0) 0.0796

GRAVY Index-0.33

Hydrophobic Moment 0.32

Boman Index-0.04

Instability Index41.35

Aliphatic Index 28.00

Aromaticity 0.1143

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1504.75

LogP -17.87

H-bond Donors 59.0

H-bond Acceptors 58.0

Rotatable Bonds 121.0

Heavy Atoms 262.0

Ring Count 7.0

Amide Bonds 35.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0240852 VERIFIED: YES

Provenance & Taxonomy

OrganismMustela putorius [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)