Peptide Database

Peptide Name[D-Ala2,F5,Phe4]dynorphin-(1-17)-NH2

Function Ontology

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid

Neurological / Signaling ▸ Neuropeptide activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC100H157N31O23

DescriptionStandard

        YAGFLRRIRPKLKWDNQ
    

Molecular Weight2161.51 Da

Isoelectric Point (pI)11.00

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.2211

GRAVY Index-1.14

Hydrophobic Moment 0.62

Boman Index-0.36

Instability Index65.27

Aliphatic Index 74.71

Aromaticity 0.1765

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 917.37

LogP -5.97

H-bond Donors 33.0

H-bond Acceptors 27.0

Rotatable Bonds 71.0

Heavy Atoms 154.0

Ring Count 5.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0198648 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Receptor agonist Opioid Analgesic Neuropeptide activity

Targetκ receptor (Mouse)