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MYP_167081
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Basic Information
Aurein 3.2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
17 amino acids
C82H137N21O22
Standard
Sequence
GLFDIVKKIAGHIASSI
Physicochemical Analysis
1769.09 Da
8.60
0.85
0.59
0.0498
0.91
0.60
0.38
42.16
143.53
0.0588
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
687.40
-4.73
24.0
24.0
60.0
125.0
2.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0070327 VERIFIED: YES
Provenance & Taxonomy
Litoria aurea [Animal]
Aurein
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Anti-Gram-positive
Staphylococcus aureus
PMID10951191 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10951191/
RECORD: Rec_0076919 VERIFIED: YES
Provenance & Taxonomy
Litoria raniformis [Animal]
Aurein
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Anti-Gram-positive
Staphylococcus aureus
50 μg/mL
MIC
PMID10951191 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10951191/
RECORD: Rec_0100997 VERIFIED: YES
Provenance & Taxonomy
Litoria raniformis [Animal]
Aurein
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Anti-Gram-positive
Staphylococcus epidermidis
50 μg/mL
MIC
PMID10951191 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10951191/
RECORD: Rec_0104825 VERIFIED: YES
Provenance & Taxonomy
Litoria raniformis [Animal]
Aurein
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
28.31 μM
MIC
PaperM.A. Apponyi et al. / Peptides 25 (2004) 1035-1054. Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance PMID15203252 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15203252/
RECORD: Rec_0109904 VERIFIED: YES
Provenance & Taxonomy
Litoria aurea [Animal]
Aurein
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Anti-Gram-positive
Micrococcus luteus
PMID10951191 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10951191/
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