Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length263 amino acids

Chemical FormulaC1355H2118N344O383S7

DescriptionStandard

        MEKPILKKLNEMLCPIITGEVEALNANLSMLEVLRKIDNYTLLDYSLISSPEITENYFDLNLKGVFYPLKSLRYPPFPSVPFVLPERSDSMLYIGISEYFFKSASYAYFTAGAFSFTLTTKEISNHLLHNSQAHGNMLSRVASTNVALAILGQRLICSLSLNRFRLSLPESNRGNIEVLRFENILSSILHFGVLPLANAKLQQGFPLPNPHKISLVNSDIEVLEGFLLISTDLKYKTSKQQPGFHGWEDLHLISGQWSGKPTP
    

Molecular Weight29579.84 Da

Isoelectric Point (pI)7.06

Net Charge (pH 7.0)0.12

Net Charge (pH 7.4) -0.55

Charge Density (pH 7.0) 0.0005

GRAVY Index0.01

Hydrophobic Moment 0.66

Boman Index0.12

Instability Index44.70

Aliphatic Index 104.18

Aromaticity 0.1027

Extinction Coeff. Reduced 25900.00

Extinction Coeff. Oxidized 26025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0205780 VERIFIED: NO

Provenance & Taxonomy

OrganismBos mutus grunniens (Wild yak) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria