Peptide Database

Peptide NameEndolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Lyase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length165 amino acids

Chemical FormulaC831H1293N245O235S3

DescriptionStandard

        MPVINTHQNIAAFLDMLAYSEGTANHPLTKNRGYDVIVTGLDGRPEIFTDYSDHPFAHGRPPKVFNRRGEKSTASGRYQQLYLFWPHYQKQLALPDFSPLSQDKLAIQLIRERGALDDIRAGRIERAVSRCRNIWASLPGAGYGQREHGLEKLVTIWRTAGGVVA
    

Molecular Weight18571.85 Da

Isoelectric Point (pI)9.51

Net Charge (pH 7.0)5.03

Net Charge (pH 7.4) 4.46

Charge Density (pH 7.0) 0.0305

GRAVY Index-0.46

Hydrophobic Moment 0.81

Boman Index-0.04

Instability Index35.40

Aliphatic Index 82.24

Aromaticity 0.0970

Extinction Coeff. Reduced 26930.00

Extinction Coeff. Oxidized 26930.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7717.24

LogP -74.96

H-bond Donors 270.0

H-bond Acceptors 249.0

Rotatable Bonds 603.0

Heavy Atoms 1314.0

Ring Count 35.0

Amide Bonds 178.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0387070 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia phage 186 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic