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MYP_167001
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Basic Information
Pro-apoptotic peptide AMD, PAP AMD
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
14 amino acids
C72H138N20O15
Standard
Sequence
KLAKLAKKLAKLAK
Physicochemical Analysis
1523.99 Da
10.70
5.75
5.54
0.4110
-0.07
0.78
-0.16
-14.97
140.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
597.74
-2.26
21.0
21.0
59.0
107.0
0.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0045182 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein transduction domain
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
MCA205
<50 μM
LC50
PMID11691780 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11691780/
RECORD: Rec_0060819 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
0.5
MIC
PMID24803240 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24803240/
RECORD: Rec_0071602 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
human red blood cells
Hemolysis
PMID24803240 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24803240/
RECORD: Rec_0071761 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
150 μg/mL
MIC
PMID23345420;26734838;24098573;33335804;8759631 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23345420/
RECORD: Rec_0076093 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Mucor circinelloides
600 μg/mL
MFC
PMID23345420;26734838;24098573;33335804;8759631 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23345420/
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