Peptide Database

Peptide NamePaneth cell-specific alpha-defensin 12

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length98 amino acids

Chemical FormulaC440H738N136O142S9

DescriptionStandard

        MRTLALLATLLLLVFQAQTQNLEKADDQVSAQDQPGAEVQDMTISFAGDKRSARGASKGITGTATCTCRHSNSCLSHERGSGMCISKKGKAYKLCCLR
    

Molecular Weight10493.98 Da

Isoelectric Point (pI)9.05

Net Charge (pH 7.0)4.62

Net Charge (pH 7.4) 4.20

Charge Density (pH 7.0) 0.0472

GRAVY Index-0.26

Hydrophobic Moment 0.77

Boman Index-0.07

Instability Index24.25

Aliphatic Index 75.82

Aromaticity 0.0306

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4538.48

LogP -58.95

H-bond Donors 166.0

H-bond Acceptors 158.0

Rotatable Bonds 363.0

Heavy Atoms 727.0

Ring Count 6.0

Amide Bonds 106.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0194434 VERIFIED: YES

Provenance & Taxonomy

OrganismEquus caballus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic Non-ribosomal