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MYP_166973
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Basic Information
W10 (Bac2A variant through single amino acid substitution)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
12 amino acids
C69H121N25O13
Standard
Sequence
RLARIVVIRWAR
Physicochemical Analysis
1508.86 Da
12.00
3.76
3.56
0.3133
0.49
0.43
-0.17
37.30
162.50
0.0833
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
646.81
-3.00
26.0
17.0
49.0
107.0
2.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0001232 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus epidermidis
2 μg/mL
MIC
PaperHigh-throughput generation of small antibacterial peptides with improved activity. Nat Biotechnol. 2005 Aug;23(8):1008-1012. doi: 10.1038/nbt1113. PMID: 16041366. PMID16041366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16041366/
RECORD: Rec_0047857 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Enterococcus faecalis ATCC29212
4 μM
MIC
PaperHigh-throughput generation of small antibacterial peptides with improved activity PMID16041366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16041366/
RECORD: Rec_0050736 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Enterococcus faecalis
4 μg/mL
MIC
PaperHigh-throughput generation of small antibacterial peptides with improved activity. Nat Biotechnol. 2005 Aug;23(8):1008-1012. doi: 10.1038/nbt1113. PMID: 16041366. PMID16041366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16041366/
RECORD: Rec_0073986 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans
8 μg/mL
MIC
PaperHigh-throughput generation of small antibacterial peptides with improved activity. Nat Biotechnol. 2005 Aug;23(8):1008-1012. doi: 10.1038/nbt1113. PMID: 16041366. PMID16041366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16041366/
RECORD: Rec_0080733 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Pseudomonas aeruginosa
16 μg/mL
MIC
PaperHigh-throughput generation of small antibacterial peptides with improved activity. Nat Biotechnol. 2005 Aug;23(8):1008-1012. doi: 10.1038/nbt1113. PMID: 16041366. PMID16041366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16041366/
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