Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC542H879N153O170S4

DescriptionStandard

        PDLSGYEKSGLGNVKYNISRIHVTAVEFHSASISLIPGTRVKLVIGNASLTIDMNWNIRTWMFKDSGRSTVYVSKVSVTAMLSTTLDNTGHTSISLTSCRTTSGDIDIKLNGKH
    

Molecular Weight12386.96 Da

Isoelectric Point (pI)9.48

Net Charge (pH 7.0)4.30

Net Charge (pH 7.4) 4.00

Charge Density (pH 7.0) 0.0377

GRAVY Index-0.10

Hydrophobic Moment 0.53

Boman Index0.06

Instability Index14.01

Aliphatic Index 91.40

Aromaticity 0.0614

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5214.17

LogP -62.76

H-bond Donors 190.0

H-bond Acceptors 182.0

Rotatable Bonds 414.0

Heavy Atoms 869.0

Ring Count 15.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0088520 VERIFIED: NO

Provenance & Taxonomy

OrganismBalaeniceps rex [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria