Peptide Database

Peptide Namebeta-Defensin, DEFB30

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC174H287N53O52S6

DescriptionStandard

        KQCIALEGVCRDKLCSTLDDTIGICNEGKKCCRRWW
    

Molecular Weight4145.85 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)1.71

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0474

GRAVY Index-0.36

Hydrophobic Moment 0.71

Boman Index-0.16

Instability Index32.41

Aliphatic Index 75.83

Aromaticity 0.0556

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1736.55

LogP -17.41

H-bond Donors 68.0

H-bond Acceptors 60.0

Rotatable Bonds 142.0

Heavy Atoms 285.0

Ring Count 4.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0173873 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3-31; 10-25; 15-32

Bio-Activity Profile

Function

Antimicrobial