Peptide Database

Peptide NameConotoxin Lt1.2

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC78H134N32O24S4

DescriptionStandard

        GCCARAACAGIHQELCGGRR
    

Molecular Weight2032.36 Da

Isoelectric Point (pI)8.57

Net Charge (pH 7.0)1.81

Net Charge (pH 7.4) 1.50

Charge Density (pH 7.0) 0.0905

GRAVY Index0.01

Hydrophobic Moment 0.47

Boman Index-0.08

Instability Index77.83

Aliphatic Index 59.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 910.99

LogP -13.09

H-bond Donors 37.0

H-bond Acceptors 31.0

Rotatable Bonds 67.0

Heavy Atoms 138.0

Ring Count 1.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0288709 VERIFIED: NO

Provenance & Taxonomy

OrganismConus litteratus [Animal]

FamilyConotoxin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0392405 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 35.0%, E 0.0%, T 25.0%, C 40.0% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic