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MYP_166940
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Basic Information
Nisin U (Bacteriocin)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
31 amino acids
C134H226N36O40S6
Standard
Sequence
ITSKSLCTPGCKTGILMTCPLKTATCGCHFG
Physicochemical Analysis
3173.84 Da
8.78
2.79
2.46
0.0902
0.45
0.37
0.21
30.65
66.13
0.0323
0.00
250.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1187.32
-15.00
47.0
50.0
101.0
216.0
4.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0210882 VERIFIED: YES
Provenance & Taxonomy
Lactococcus uberis [Bacterium]
Bacteriocin
Structure & Mods
thioether-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
There are two dihydroalanines (Dha)(S5; T18), one didehydrobutyrine (Dhb)(T2), one lanthionine (S3-C7) and four methyllanthionines (T8-C11; T13-C19; T23-C26; T25-C28)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Streptococcus uberis
PaperPubMed PMID: 16461661 PMID16461661 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16461661/
RECORD: Rec_0241571 VERIFIED: YES
Provenance & Taxonomy
Streptococcus uberis [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ1884
RECORD: Rec_0292493 VERIFIED: YES
Provenance & Taxonomy
Lactococcus uberis [Bacterium]
Bacteriocin
Structure & Mods
thioether-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
There are two dihydroalanines (Dha)(S5; T18), one didehydrobutyrine (Dhb)(T2), one lanthionine (S3-C7) and four methyllanthionines (T8-C11; T13-C19; T23-C26; T25-C28)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Streptococcus pyogenes
PaperPubMed PMID: 16461661 PMID16461661 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16461661/
RECORD: Rec_0313070 VERIFIED: YES
Provenance & Taxonomy
Lactococcus uberis [Bacterium]
Bacteriocin
Structure & Mods
thioether-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
There are two dihydroalanines (Dha)(S5; T18), one didehydrobutyrine (Dhb)(T2), one lanthionine (S3-C7) and four methyllanthionines (T8-C11; T13-C19; T23-C26; T25-C28)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Streptococcus mitis
PaperPubMed PMID: 16461661 PMID16461661 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16461661/
RECORD: Rec_0328771 VERIFIED: YES
Provenance & Taxonomy
Lactococcus uberis [Bacterium]
Bacteriocin
Structure & Mods
thioether-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
There are two dihydroalanines (Dha)(S5; T18), one didehydrobutyrine (Dhb)(T2), one lanthionine (S3-C7) and four methyllanthionines (T8-C11; T13-C19; T23-C26; T25-C28)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus simulans
PaperPubMed PMID: 16461661 PMID16461661 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16461661/
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