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MYP_166940
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Basic Information
Nisin U (Bacteriocin)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
31 amino acids
C134H226N36O40S6
Standard
Sequence
ITSKSLCTPGCKTGILMTCPLKTATCGCHFG
Physicochemical Analysis
3173.84 Da
8.78
2.79
2.46
0.0902
0.45
0.37
0.21
30.65
66.13
0.0323
0.00
250.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1187.32
-15.00
47.0
50.0
101.0
216.0
4.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0003592 VERIFIED: YES
Provenance & Taxonomy
Lactococcus uberis [Bacterium]
Bacteriocin
Structure & Mods
thioether-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
There are two dihydroalanines (Dha)(S5; T18), one didehydrobutyrine (Dhb)(T2), one lanthionine (S3-C7) and four methyllanthionines (T8-C11; T13-C19; T23-C26; T25-C28)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Lactococcus lactis
PaperPubMed PMID: 16461661 PMID16461661 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16461661/
RECORD: Rec_0031056 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0066441 VERIFIED: YES
Provenance & Taxonomy
Lactococcus uberis [Bacterium]
Bacteriocin
Structure & Mods
thioether-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
There are two dihydroalanines (Dha)(S5; T18), one didehydrobutyrine (Dhb)(T2), one lanthionine (S3-C7) and four methyllanthionines (T8-C11; T13-C19; T23-C26; T25-C28)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Streptococcus agalactiae
PaperPubMed PMID: 16461661 PMID16461661 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16461661/
RECORD: Rec_0113606 VERIFIED: YES
Provenance & Taxonomy
Lactococcus uberis [Bacterium]
Bacteriocin
Structure & Mods
thioether-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
There are two dihydroalanines (Dha)(S5; T18), one didehydrobutyrine (Dhb)(T2), one lanthionine (S3-C7) and four methyllanthionines (T8-C11; T13-C19; T23-C26; T25-C28)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Streptococcus dysgalactiae
PaperPubMed PMID: 16461661 PMID16461661 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16461661/
RECORD: Rec_0136810 VERIFIED: YES
Provenance & Taxonomy
Lactococcus uberis [Bacterium]
Bacteriocin
Structure & Mods
thioether-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
There are two dihydroalanines (Dha)(S5; T18), one didehydrobutyrine (Dhb)(T2), one lanthionine (S3-C7) and four methyllanthionines (T8-C11; T13-C19; T23-C26; T25-C28)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Lactobacillus acidophilus
PaperPubMed PMID: 16461661 PMID16461661 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16461661/
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