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MYP_166934
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Basic Information
Buforin-EC
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
16 amino acids
C85H147N31O17
Standard
Sequence
RAGLKFPVGRVHRLLR
Physicochemical Analysis
1875.27 Da
12.00
4.85
4.59
0.3029
-0.19
0.60
-0.24
34.88
115.62
0.0625
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
793.33
-5.70
30.0
23.0
62.0
133.0
3.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0047141 VERIFIED: YES
Provenance & Taxonomy
Euphlyctis cyanophlyctis [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Micrococcus luteus PTCC1625
6.0 μM
MIC
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ3843
RECORD: Rec_0064040 VERIFIED: YES
Provenance & Taxonomy
Euphlyctis cyanophlyctis [Animal]
Buforin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli HP101BA 7601c
9.6 μM
MIC
PaperIdentification and Characterization of Novel Antibacterial Peptides from Skin Secretions of Euphlyctis cyanophlyctis
RECORD: Rec_0080421 VERIFIED: NO
Provenance & Taxonomy
Euphlyctis cyanophlyctis [Animal]
Histone H2A
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Amphibian defense peptide Antibiotic Antimicrobial Hemolytic Non-ribosomal
Qualitative functional evidence
Evidence URLhttps://www.uniprot.org/uniprotkb/C0HJB7/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0100214 VERIFIED: YES
Provenance & Taxonomy
Euphlyctis cyanophlyctis [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Micrococcus luteus PTCC1625
6 μM
MIC
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP01833
RECORD: Rec_0103987 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
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