Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length203 amino acids

Chemical FormulaC1058H1585N231O304S10

DescriptionStandard

        IDDLAEIDYSLNSLPAVFRPFIDLDLKGIVYPAGNYTGPPYVATPFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITVAEEVKSGKLICFLFCLFWFFFLQTCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPIISLEQDSFTVEIQGSMEVFAVLPDSTTQSLFTMNIAANTSIALNIFDQKLMGSLCLNR
    

Molecular Weight22724.92 Da

Isoelectric Point (pI)4.09

Net Charge (pH 7.0)-12.26

Net Charge (pH 7.4) -12.57

Charge Density (pH 7.0) -0.0604

GRAVY Index0.44

Hydrophobic Moment 0.60

Boman Index0.29

Instability Index44.07

Aliphatic Index 96.11

Aromaticity 0.1576

Extinction Coeff. Reduced 21890.00

Extinction Coeff. Oxidized 22140.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0076107 VERIFIED: NO

Provenance & Taxonomy

OrganismChunga burmeisteri [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria