MYP_166916
Ecumicin
Antimicrobial
Antimicrobial
▸
Antibacterial
▸
Anti-Mycobacterium
Standard
13 amino acids
C75H120N14O16
Standard
VVITTVLVVWVFV
1473.84 Da
5.50
-0.27
-0.48
-0.0205
2.94
0.14
0.92
2.70
216.15
0.1538
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
468.77
1.63
17.0
16.0
42.0
105.0
3.0
12.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0212801
VERIFIED: YES
Provenance & Taxonomy
Nonomuraea sp. [Bacterium]
Nonribosomal peptide
Structure & Mods
macrocyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
N-methylation pattern, N-Me-Val = N-methyl-valine, N,N-Me2-Val = N,N-dimethyl-valine, N-Me-Thr = N-methyl-threonine, N-Me-Leu = N-methyl-leucine, N-Me-allo-Ilu = N-methyl-isoleucine, N-Me-4-OMe-Trp = N-methyl-4-methoxy-tryptophan, Ph-threo-Ser = Phe
Bio-Activity Profile
Antimicrobial
Antimycobacterial
Mycobacterium kansasii (ATCC 12478)
0.24 μM
MIC
RECORD: Rec_0212856
VERIFIED: YES
Provenance & Taxonomy
Nonomuraea sp. [Bacterium]
Nonribosomal peptide
Structure & Mods
macrocyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
N-methylation pattern, N-Me-Val = N-methyl-valine, N,N-Me2-Val = N,N-dimethyl-valine, N-Me-Thr = N-methyl-threonine, N-Me-Leu = N-methyl-leucine, N-Me-allo-Ilu = N-methyl-isoleucine, N-Me-4-OMe-Trp = N-methyl-4-methoxy-tryptophan, Ph-threo-Ser = Phe
Bio-Activity Profile
Antimicrobial
Antimycobacterial
Mycobacterium Tuberculosis H37Rv resistant to cycloserine
MIC
RECORD: Rec_0223448
VERIFIED: YES
Provenance & Taxonomy
Nonomuraea sp. [Bacterium]
Nonribosomal peptide
Structure & Mods
macrocyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
N-methylation pattern, N-Me-Val = N-methyl-valine, N,N-Me2-Val = N,N-dimethyl-valine, N-Me-Thr = N-methyl-threonine, N-Me-Leu = N-methyl-leucine, N-Me-allo-Ilu = N-methyl-isoleucine, N-Me-4-OMe-Trp = N-methyl-4-methoxy-tryptophan, Ph-threo-Ser = Phe
Bio-Activity Profile
Antimicrobial
Antimycobacterial
Single nucleotide polymorphism (SNP) clusters: X004439 and X004244 to the East Asian lineage
0.13-0.38 μM
MIC
RECORD: Rec_0225138
VERIFIED: YES
Provenance & Taxonomy
Nonomuraea sp. [Bacterium]
Nonribosomal peptide
Structure & Mods
macrocyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
N-methylation pattern, N-Me-Val = N-methyl-valine, N,N-Me2-Val = N,N-dimethyl-valine, N-Me-Thr = N-methyl-threonine, N-Me-Leu = N-methyl-leucine, N-Me-allo-Ilu = N-methyl-isoleucine, N-Me-4-OMe-Trp = N-methyl-4-methoxy-tryptophan, Ph-threo-Ser = Phe
Bio-Activity Profile
Antimicrobial
Antimycobacterial
Single nucleotide polymorphism (SNP) clusters: X001354 to the East African Indian lineage
0.13-0.38 μM
MIC
RECORD: Rec_0232740
VERIFIED: YES
Provenance & Taxonomy
Nonomuraea sp. [Bacterium]
Nonribosomal peptide
Structure & Mods
macrocyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
N-methylation pattern, N-Me-Val = N-methyl-valine, N,N-Me2-Val = N,N-dimethyl-valine, N-Me-Thr = N-methyl-threonine, N-Me-Leu = N-methyl-leucine, N-Me-allo-Ilu = N-methyl-isoleucine, N-Me-4-OMe-Trp = N-methyl-4-methoxy-tryptophan, Ph-threo-Ser = Phe
Bio-Activity Profile
Antimicrobial
Antimycobacterial
Mycobacterium avium (ATCC 15769)
0.35 μM
MIC
Showing 5 records on this page · Page 3 of 5