MYP_166916
Ecumicin
Antimicrobial
Antimicrobial
▸
Antibacterial
▸
Anti-Mycobacterium
Standard
13 amino acids
C75H120N14O16
Standard
VVITTVLVVWVFV
1473.84 Da
5.50
-0.27
-0.48
-0.0205
2.94
0.14
0.92
2.70
216.15
0.1538
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
468.77
1.63
17.0
16.0
42.0
105.0
3.0
12.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0110799
VERIFIED: YES
Provenance & Taxonomy
Nonomuraea sp. [Bacterium]
Nonribosomal peptide
Structure & Mods
macrocyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
N-methylation pattern, N-Me-Val = N-methyl-valine, N,N-Me2-Val = N,N-dimethyl-valine, N-Me-Thr = N-methyl-threonine, N-Me-Leu = N-methyl-leucine, N-Me-allo-Ilu = N-methyl-isoleucine, N-Me-4-OMe-Trp = N-methyl-4-methoxy-tryptophan, Ph-threo-Ser = Phe
Bio-Activity Profile
Antimicrobial
Antimycobacterial
Single nucleotide polymorphism (SNP) clusters: X005282 and X005319 to the Euro-American lineage
0.13-0.38 μM
MIC
RECORD: Rec_0129781
VERIFIED: YES
Provenance & Taxonomy
Nonomuraea sp. [Bacterium]
Nonribosomal peptide
Structure & Mods
macrocyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
N-methylation pattern, N-Me-Val = N-methyl-valine, N,N-Me2-Val = N,N-dimethyl-valine, N-Me-Thr = N-methyl-threonine, N-Me-Leu = N-methyl-leucine, N-Me-allo-Ilu = N-methyl-isoleucine, N-Me-4-OMe-Trp = N-methyl-4-methoxy-tryptophan, Ph-threo-Ser = Phe
Bio-Activity Profile
Antimicrobial
Antimycobacterial
Mycobacterium tuberculosis Erdman (ATCC 35801)
0.16 μM
MIC
RECORD: Rec_0131639
VERIFIED: YES
Provenance & Taxonomy
Nonomuraea sp. [Bacterium]
Nonribosomal peptide
Structure & Mods
macrocyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
N-methylation pattern, N-Me-Val = N-methyl-valine, N,N-Me2-Val = N,N-dimethyl-valine, N-Me-Thr = N-methyl-threonine, N-Me-Leu = N-methyl-leucine, N-Me-allo-Ilu = N-methyl-isoleucine, N-Me-4-OMe-Trp = N-methyl-4-methoxy-tryptophan, Ph-threo-Ser = Phe
Bio-Activity Profile
Antimicrobial
Antimycobacterial
Mycobacterium tuberculosis H37Rv strains with monoresistance to cycloserine (CS) (ATCC 35826)
0.12 μM
MIC
RECORD: Rec_0171575
VERIFIED: YES
Provenance & Taxonomy
Nonomuraea sp. [Bacterium]
Nonribosomal peptide
Structure & Mods
macrocyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
N-methylation pattern, N-Me-Val = N-methyl-valine, N,N-Me2-Val = N,N-dimethyl-valine, N-Me-Thr = N-methyl-threonine, N-Me-Leu = N-methyl-leucine, N-Me-allo-Ilu = N-methyl-isoleucine, N-Me-4-OMe-Trp = N-methyl-4-methoxy-tryptophan, Ph-threo-Ser = Phe
Bio-Activity Profile
Antimicrobial
Antimycobacterial
Mycobacterium abscessus (ATCC 19977)
63 μM
MIC
RECORD: Rec_0183420
VERIFIED: YES
Provenance & Taxonomy
Nonomuraea sp. [Bacterium]
Nonribosomal peptide
Structure & Mods
macrocyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
N-methylation pattern, N-Me-Val = N-methyl-valine, N,N-Me2-Val = N,N-dimethyl-valine, N-Me-Thr = N-methyl-threonine, N-Me-Leu = N-methyl-leucine, N-Me-allo-Ilu = N-methyl-isoleucine, N-Me-4-OMe-Trp = N-methyl-4-methoxy-tryptophan, Ph-threo-Ser = Phe
Bio-Activity Profile
Antimicrobial
Antimycobacterial
Mycobacterium tuberculosis H37Rv strains with monoresistance to rifampin (RMP) (ATCC 35838)
0.19 μM
MIC
Showing 5 records on this page · Page 2 of 5