MYP_166916
Ecumicin
Antimicrobial
Antimicrobial
▸
Antibacterial
▸
Anti-Mycobacterium
Standard
13 amino acids
C75H120N14O16
Standard
VVITTVLVVWVFV
1473.84 Da
5.50
-0.27
-0.48
-0.0205
2.94
0.14
0.92
2.70
216.15
0.1538
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
468.77
1.63
17.0
16.0
42.0
105.0
3.0
12.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0022063
VERIFIED: YES
Provenance & Taxonomy
Nonomuraea sp. [Bacterium]
Nonribosomal peptide
Structure & Mods
macrocyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
N-methylation pattern, N-Me-Val = N-methyl-valine, N,N-Me2-Val = N,N-dimethyl-valine, N-Me-Thr = N-methyl-threonine, N-Me-Leu = N-methyl-leucine, N-Me-allo-Ilu = N-methyl-isoleucine, N-Me-4-OMe-Trp = N-methyl-4-methoxy-tryptophan, Ph-threo-Ser = Phe
Bio-Activity Profile
Antimicrobial
Antimycobacterial
Mycobacterium Tuberculosis H37Rv resistant to streptomycin
MIC
RECORD: Rec_0062806
VERIFIED: YES
Provenance & Taxonomy
Nonomuraea sp. [Bacterium]
Nonribosomal peptide
Structure & Mods
macrocyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
N-methylation pattern, N-Me-Val = N-methyl-valine, N,N-Me2-Val = N,N-dimethyl-valine, N-Me-Thr = N-methyl-threonine, N-Me-Leu = N-methyl-leucine, N-Me-allo-Ilu = N-methyl-isoleucine, N-Me-4-OMe-Trp = N-methyl-4-methoxy-tryptophan, Ph-threo-Ser = Phe
Bio-Activity Profile
Antimicrobial
Antimycobacterial
Mycobaterium tuberculosis XDR
0.31-0.62 μM
MIC
RECORD: Rec_0085012
VERIFIED: YES
Provenance & Taxonomy
Nonomuraea sp. [Bacterium]
Nonribosomal peptide
Structure & Mods
macrocyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
N-methylation pattern, N-Me-Val = N-methyl-valine, N,N-Me2-Val = N,N-dimethyl-valine, N-Me-Thr = N-methyl-threonine, N-Me-Leu = N-methyl-leucine, N-Me-allo-Ilu = N-methyl-isoleucine, N-Me-4-OMe-Trp = N-methyl-4-methoxy-tryptophan, Ph-threo-Ser = Phe
Bio-Activity Profile
Antimicrobial
Antimycobacterial
Mycobaterium tuberculosis MDR
0.31 μM
MIC
RECORD: Rec_0087606
VERIFIED: YES
Provenance & Taxonomy
Nonomuraea sp. [Bacterium]
Nonribosomal peptide
Structure & Mods
macrocyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
N-methylation pattern, N-Me-Val = N-methyl-valine, N,N-Me2-Val = N,N-dimethyl-valine, N-Me-Thr = N-methyl-threonine, N-Me-Leu = N-methyl-leucine, N-Me-allo-Ilu = N-methyl-isoleucine, N-Me-4-OMe-Trp = N-methyl-4-methoxy-tryptophan, Ph-threo-Ser = Phe
Bio-Activity Profile
Antimicrobial
Antimycobacterial
Mycobacterium tuberculosis strain H37Rv (ATCC 27294)
0.16 μM
MIC
RECORD: Rec_0105955
VERIFIED: YES
Provenance & Taxonomy
Nonomuraea sp. [Bacterium]
Nonribosomal peptide
Structure & Mods
macrocyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
N-methylation pattern, N-Me-Val = N-methyl-valine, N,N-Me2-Val = N,N-dimethyl-valine, N-Me-Thr = N-methyl-threonine, N-Me-Leu = N-methyl-leucine, N-Me-allo-Ilu = N-methyl-isoleucine, N-Me-4-OMe-Trp = N-methyl-4-methoxy-tryptophan, Ph-threo-Ser = Phe
Bio-Activity Profile
Antimicrobial
Antimycobacterial
Single nucleotide polymorphism (SNP) clusters: X001354 corresponding to the Indo-Oceanic lineage,
0.13-0.38 μM
MIC
Showing 5 records on this page · Page 1 of 5