Peptide Database

Peptide NameGlutenin-Glt-17 (p46-p60; E52 and 53)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC78H117N21O27

DescriptionStandard

        QQPPFSEEQQQPLPQ
    

Molecular Weight1780.89 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.23

Net Charge (pH 7.4) -2.44

Charge Density (pH 7.0) -0.1490

GRAVY Index-1.91

Hydrophobic Moment 0.27

Boman Index-0.27

Instability Index172.31

Aliphatic Index 26.00

Aromaticity 0.0667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 788.93

LogP -9.19

H-bond Donors 21.0

H-bond Acceptors 25.0

Rotatable Bonds 54.0

Heavy Atoms 126.0

Ring Count 5.0

Amide Bonds 20.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0139600 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGlutenin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E52

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman gluten-specific T cells / HLA-DQ2

MethodT-cell proliferation assay