‹ ›
MYP_166869
← PREVIOUS NEXT → BACK
Basic Information
Unnamed
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C90H141N31O20S4
Standard
Sequence
RGGRLCYCRGWICFCVGR
Physicochemical Analysis
2105.54 Da
9.37
3.72
3.46
0.2066
0.19
0.40
-0.07
4.82
59.44
0.1667
6990.00
7240.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
841.64
-7.40
37.0
28.0
66.0
145.0
4.0
17.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0297430 VERIFIED: NO
Provenance & Taxonomy
Sus scrofa [Animal]
Cathelicidin
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperProtegrin-4 Evidence URLhttps://www.uniprot.org/uniprotkb/P49933/entry
RECORD: Rec_0340526 VERIFIED: NO
Provenance & Taxonomy
Sus scrofa [Animal]
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0345020 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
80 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/18455267/ PMID18455267 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18455267/
RECORD: Rec_0385020 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Cathelicidin
9823
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Two disulfide bridges:6,15; 8,13;
Bio-Activity Profile
Antimicrobial Antiviral
PaperIdentification of a new member of the protegrin family by cDNA cloning.
RECORD: Rec_0401952 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Protegrin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
FIRST PREV 1 2
Showing 5 records on this page · Page 2 of 2