Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC884H1404N260O264S11

DescriptionStandard

        MKKGIIACSIAAIISLAATLWPQALRTSPEAQLKMAKYEDCRKTPYYCPAGVLTVGIGSTSKVENREHTNSEIAERWVNDLMRAEKCTNREFNGAAAPQKVFESMTDANFNVGCTGLGWYTTKDGQKVRTTLWRHAQAGNWKGVCERLTDFVNSAGKRSQGLVNRRTDFQAWCLSDPALKGAK
    

Molecular Weight20250.90 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)8.62

Net Charge (pH 7.4) 8.16

Charge Density (pH 7.0) 0.0471

GRAVY Index-0.45

Hydrophobic Moment 0.83

Boman Index-0.07

Instability Index35.53

Aliphatic Index 67.81

Aromaticity 0.0820

Extinction Coeff. Reduced 38960.00

Extinction Coeff. Oxidized 39335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8519.26

LogP -101.29

H-bond Donors 306.0

H-bond Acceptors 286.0

Rotatable Bonds 674.0

Heavy Atoms 1419.0

Ring Count 29.0

Amide Bonds 199.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0146308 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella pneumoniae [Bacterium]

FamilyLysozyme

Tax ID573

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0280742 VERIFIED: YES

Provenance & Taxonomy

OrganismKlebsiella phage 3LV2017 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic