‹ ›
MYP_166747
← PREVIOUS NEXT → BACK
Basic Information
peptide 12 (Derived from B1)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
7 amino acids
C39H68N10O8
Standard
Sequence
AFALKKK
Physicochemical Analysis
805.02 Da
10.30
2.79
2.60
0.3990
-0.21
0.18
-0.14
-3.56
84.29
0.1429
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
315.98
-0.98
11.0
11.0
29.0
57.0
1.0
6.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0196224 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Residue 1 and residue 3 are 1-naphthylmethylglycine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
PaperCharacterization, mechanism of action and optimization of activity of a novel peptide-peptoid hybrid against bacterial pathogens involved in canine skin infections PMID30842436 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30842436/
RECORD: Rec_0197800 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Residue 1 and residue 3 are 2-naphthylmethylglycine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Hemolytic
PaperCharacterization, mechanism of action and optimization of activity of a novel peptide-peptoid hybrid against bacterial pathogens involved in canine skin infections PMID30842436 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30842436/
RECORD: Rec_0218564 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
Amidation
Residue 1 and residue 3 are 2-naphthylmethylglycine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Gram-positive bacteria: MRSP C22963
8 μg/mL
MIC
PaperCharacterization, mechanism of action and optimization of activity of a novel peptide-peptoid hybrid against bacterial pathogens involved in canine skin infections PMID30842436 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30842436/
RECORD: Rec_0225473 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
Amidation
Residue 1 and residue 3 are 1-naphthylmethylglycine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Hemolytic
PaperCharacterization, mechanism of action and optimization of activity of a novel peptide-peptoid hybrid against bacterial pathogens involved in canine skin infections PMID30842436 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30842436/
RECORD: Rec_0261176 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
Amidation
Residue 1 and residue 3 are 1-naphthylmethylglycine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Gram-positive bacteria: MRSP C22963
16 μg/mL
MIC
PaperCharacterization, mechanism of action and optimization of activity of a novel peptide-peptoid hybrid against bacterial pathogens involved in canine skin infections PMID30842436 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30842436/
FIRST PREV 1 2 3 4 NEXT LAST
Showing 5 records on this page · Page 2 of 4