Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC470H774N130O114S7

DescriptionStandard

        MKFLLGLVLKLKLLIEKFIRKGRSGLGSSESQCIALGGHCRRPVCKLIEEHIGNCLRKTKCCRKWWILIPVPTPLFYSEYQEPIKPRVK
    

Molecular Weight10294.43 Da

Isoelectric Point (pI)9.88

Net Charge (pH 7.0)11.62

Net Charge (pH 7.4) 11.19

Charge Density (pH 7.0) 0.1306

GRAVY Index-0.06

Hydrophobic Moment 0.77

Boman Index-0.01

Instability Index63.09

Aliphatic Index 106.18

Aromaticity 0.0787

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3914.98

LogP -24.95

H-bond Donors 144.0

H-bond Acceptors 135.0

Rotatable Bonds 349.0

Heavy Atoms 721.0

Ring Count 17.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0357515 VERIFIED: NO

Provenance & Taxonomy

OrganismSciurus vulgaris [Animal]

FamilyDefensin

Tax ID55149

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal