Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length425 amino acids

Chemical FormulaC2129H3307N519O615S19

DescriptionStandard

        MLPSVIAVLMLLSYTCGENPAIQVILTNKGLQYGKHTGTDWIQEILENVTLPDISGKFPIGRLGSVDYTLSGISITKVDLPEPSVEFYPNTTGLKSSMSGLSVALSGEWRTHYGIIHDGGTLDLALFSVSVMSIVELGKDANGHLSISSVTCTCTIGDVAIQFYGGASWIFRPFVPFFKGHIKGEIQSRICPKVEEVIVILEDHLQVMNATKNTLNWLFVTLNLKGELYSIRTHKEPPFEAQSFTVPQQHSYMFSVGMSEFTLNSASYGCYSDGLLQATVNDSMIPPLSPVHLNTTSMGQFIPQLPKLFPGLLMSLTVYAREVPMFSLKPDAVKLDFQGTVKAFAILPNDTQAPLFTLNVVSNFVFWTFWAEKVKIDSASFMVYSPLFTLTLIGSEVGTFQTDALENVVKMGIEMAVLPKVNGES
    

Molecular Weight46622.37 Da

Isoelectric Point (pI)5.29

Net Charge (pH 7.0)-10.72

Net Charge (pH 7.4) -11.56

Charge Density (pH 7.0) -0.0252

GRAVY Index0.23

Hydrophobic Moment 0.68

Boman Index0.22

Instability Index36.86

Aliphatic Index 97.86

Aromaticity 0.1012

Extinction Coeff. Reduced 50880.00

Extinction Coeff. Oxidized 51130.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0033148 VERIFIED: NO

Provenance & Taxonomy

OrganismMastacembelus armatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria