Peptide Database

Peptide NameConotoxin Cal14.1a

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC119H177N33O44S4

DescriptionStandard

        GIWCDPPCPKGETCRGGECSDEFNSDV
    

Molecular Weight2902.13 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-4.27

Net Charge (pH 7.4) -4.54

Charge Density (pH 7.0) -0.1581

GRAVY Index-0.78

Hydrophobic Moment 0.39

Boman Index-0.08

Instability Index34.06

Aliphatic Index 25.19

Aromaticity 0.0741

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1224.84

LogP -15.91

H-bond Donors 44.0

H-bond Acceptors 44.0

Rotatable Bonds 89.0

Heavy Atoms 200.0

Ring Count 6.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0275543 VERIFIED: NO

Provenance & Taxonomy

OrganismConus californicus [Animal]

FamilyConotoxin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0372415 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 0.0%, T 33.3%, C 66.7% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic