Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length152 amino acids

Chemical FormulaC754H1184N212O212S8

DescriptionStandard

        MGSKVMFKPRTSTEAIFVHCSATKPSMDVGRREIEMWHKQQGWLAVGYHFIIKRDGTVEEGRPVDVVGSHVKDWNHKSVGVCLVGGIDDKAKFAANFTPAQMQSLKVKLDELKALYPQAVIKAHHDVAPKACPSFDLGHWLKTGELVTSDRG
    

Molecular Weight16867.28 Da

Isoelectric Point (pI)8.99

Net Charge (pH 7.0)4.18

Net Charge (pH 7.4) 3.47

Charge Density (pH 7.0) 0.0275

GRAVY Index-0.30

Hydrophobic Moment 0.62

Boman Index0.01

Instability Index35.67

Aliphatic Index 76.91

Aromaticity 0.0789

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6750.06

LogP -61.70

H-bond Donors 236.0

H-bond Acceptors 232.0

Rotatable Bonds 560.0

Heavy Atoms 1186.0

Ring Count 31.0

Amide Bonds 158.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0002336 VERIFIED: YES

Provenance & Taxonomy

OrganismCitrobacter phage CR8 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic