Peptide Database

Peptide NameConotoxin Vx2

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC89H127N25O32S6

DescriptionStandard

        WIDPSHYCCCGGGCTDDCVNC
    

Molecular Weight2251.50 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-3.21

Net Charge (pH 7.4) -3.55

Charge Density (pH 7.0) -0.1528

GRAVY Index0.00

Hydrophobic Moment 0.24

Boman Index0.13

Instability Index61.93

Aliphatic Index 32.38

Aromaticity 0.0952

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 896.68

LogP -11.91

H-bond Donors 36.0

H-bond Acceptors 36.0

Rotatable Bonds 65.0

Heavy Atoms 152.0

Ring Count 5.0

Amide Bonds 21.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0253832 VERIFIED: NO

Provenance & Taxonomy

OrganismConus vexillum [Animal]

FamilyConotoxin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide8-21; 9-14; 10-18

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0376169 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 9.5%, T 52.4%, C 38.1% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic