Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length349 amino acids

Chemical FormulaC1700H2696N460O500S12

DescriptionStandard

        MLSLLILLLNLTNHAFGQNPAIKAILSNKGLQYGSHIGADWMQEKIGSVIIPDVRGGVDIGIGTVHYVLDGISVSGCDVPEPSVEFYEGVGLKAVISGLSISMSGNWHTRFGIITDGGSFDLAVFNVDVTSVVQIGSDQSGHISISSENCDASVGEASINFHGGASLIFQPFVSLFHHRIKAIIEERICPLVEEHVTDLERHLSEMQVSFKVNSALVLDVPLTNSPLVDSISLGLDLKGEFYSVQSHTDPPFKAEPFNLPEDKGHMLSLGLSEFTVNSASYAYFSAGLLQAQINDSMVCVHVCVGNRSPYKDSKTRKIAILGLEVRFRVTIRVRFRIMAKVRVKLRVRG
    

Molecular Weight37963.15 Da

Isoelectric Point (pI)6.10

Net Charge (pH 7.0)-5.37

Net Charge (pH 7.4) -6.39

Charge Density (pH 7.0) -0.0154

GRAVY Index0.18

Hydrophobic Moment 0.62

Boman Index0.15

Instability Index34.93

Aliphatic Index 105.47

Aromaticity 0.0745

Extinction Coeff. Reduced 21430.00

Extinction Coeff. Oxidized 21680.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0039546 VERIFIED: YES

Provenance & Taxonomy

OrganismOncorhynchus mykiss [Animal]

FamilyBPI/LBP

Tax ID8022

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria