Peptide Database

Peptide NameNeurotensin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC70H116N22O18

DescriptionStandard

        EAHISKARRPYIL
    

Molecular Weight1553.81 Da

Isoelectric Point (pI)9.99

Net Charge (pH 7.0)1.92

Net Charge (pH 7.4) 1.70

Charge Density (pH 7.0) 0.1478

GRAVY Index-0.53

Hydrophobic Moment 0.40

Boman Index-0.19

Instability Index110.19

Aliphatic Index 105.38

Aromaticity 0.0769

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 659.99

LogP -4.67

H-bond Donors 24.0

H-bond Acceptors 21.0

Rotatable Bonds 50.0

Heavy Atoms 110.0

Ring Count 3.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0124340 VERIFIED: YES

Provenance & Taxonomy

OrganismPelophylax ridibundus [Animal]

FamilyNeurotensin

Tax ID8406

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

Bio-Activity Profile

Function

Neuropeptide Hormone

RECORD: Rec_0178156 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0249696 VERIFIED: YES

Provenance & Taxonomy

OrganismPelophylax ridibundus [Animal]

FamilyNeurotensin

Tax ID8406

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Bio-Activity Profile

Function

-

Half-LifeMammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour