Peptide Database

Peptide NameMouse beta-defensin-14

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC156H269N49O41S4

DescriptionStandard

        LRKYYCKIRSGRCALIGCLPKEKQIGRCSLTG
    

Molecular Weight3615.37 Da

Isoelectric Point (pI)9.85

Net Charge (pH 7.0)6.72

Net Charge (pH 7.4) 6.45

Charge Density (pH 7.0) 0.2099

GRAVY Index-0.26

Hydrophobic Moment 0.57

Boman Index-0.17

Instability Index47.41

Aliphatic Index 88.44

Aromaticity 0.0625

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1489.85

LogP -14.52

H-bond Donors 59.0

H-bond Acceptors 52.0

Rotatable Bonds 125.0

Heavy Atoms 250.0

Ring Count 3.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0101726 VERIFIED: YES

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)