Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC406H642N114O119S14

DescriptionStandard

        MKTSSVAVAVAVVLTFICLQESSAVSFTEVQELEEPMSNDGPIAAYKEMPEDSWKMGYGSRRWKCRFCCRCCPRMRGCGLCCRF
    

Molecular Weight9473.04 Da

Isoelectric Point (pI)8.10

Net Charge (pH 7.0)1.43

Net Charge (pH 7.4) 1.06

Charge Density (pH 7.0) 0.0170

GRAVY Index-0.03

Hydrophobic Moment 0.65

Boman Index-0.01

Instability Index70.95

Aliphatic Index 59.17

Aromaticity 0.0952

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3740.38

LogP -37.90

H-bond Donors 142.0

H-bond Acceptors 135.0

Rotatable Bonds 310.0

Heavy Atoms 653.0

Ring Count 14.0

Amide Bonds 86.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0152401 VERIFIED: NO

Provenance & Taxonomy

OrganismSparus aurata [Animal]

FamilyHepcidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal