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MYP_166618
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Basic Information
Grammistin Pp1 (Group II grammistin; fish, chordates, animals)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Ichthyotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
13 amino acids
C79H117N17O15
Standard
Sequence
FIGGIISFFKRLF
Physicochemical Analysis
1544.88 Da
11.00
1.76
1.55
0.1353
1.42
0.64
0.52
25.71
120.00
0.3077
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
520.67
0.02
19.0
17.0
50.0
111.0
4.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0021158 VERIFIED: YES
Provenance & Taxonomy
Pogonoperca punctata [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
dameselae subsp
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP02318
RECORD: Rec_0046551 VERIFIED: NO
Provenance & Taxonomy
Grammistes sexlineatus [Animal]
Grammistin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Cytolytic Toxin Hemolytic Ichthyotoxic Non-ribosomal
Qualitative functional evidence
PMID15777955 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15777955/; https://www.uniprot.org/uniprotkb/P69840/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0057050 VERIFIED: NO
Provenance & Taxonomy
Pogonoperca punctata [Animal]; Grammistes sexlineatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Toxin
RECORD: Rec_0059764 VERIFIED: YES
Provenance & Taxonomy
Pogonoperca punctata [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Vibrio parahaemolyticus
25 μg/mL
MIC
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP02318
RECORD: Rec_0070382 VERIFIED: YES
Provenance & Taxonomy
Pogonoperca punctata [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli JCM 1649
50 μg/mL
MIC
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP02318
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