Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC494H808N138O133S10

DescriptionStandard

        MKFLLLTLTVFLILFQMLPVCRGRKSCWIIKGHCRKDCKSGEQVKKPCRNGDYCCVPSKTVSQPQRPTQTTTRKYQTFTDKMKSNALLEQIPVIFQ
    

Molecular Weight11129.19 Da

Isoelectric Point (pI)9.79

Net Charge (pH 7.0)11.51

Net Charge (pH 7.4) 11.12

Charge Density (pH 7.0) 0.1199

GRAVY Index-0.31

Hydrophobic Moment 0.64

Boman Index-0.09

Instability Index35.38

Aliphatic Index 76.04

Aromaticity 0.0833

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4418.25

LogP -41.40

H-bond Donors 160.0

H-bond Acceptors 156.0

Rotatable Bonds 375.0

Heavy Atoms 775.0

Ring Count 16.0

Amide Bonds 105.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0295209 VERIFIED: NO

Provenance & Taxonomy

OrganismCapra hircus [Animal]

FamilyBeta-defensin; Defensin

Tax ID9925

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic