‹ ›
MYP_166600
← PREVIOUS NEXT → BACK
Basic Information
D-14
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
not Standard
24 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
RXRPRPYSPRPTSHPRPIRVCXXX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0248090 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2; ornithine at 22; non-canonical residue code at 23; non-canonical residue code at 24; peptide is the all-L and all-D form, respectively, lower case letters denote D form. suffix m = conjugate containing a control PNA with two mismatched (interchanged) nucleobases, X = 6-aminohexanoic acid = H2N-(CH2)5COOH residue, Anti-acpP: B= PNA2301 = H-CTCATACTCT-NH2, Mismatch: J = PNA3961 = H-CTCTTACACT-NH2, O = Mal= polar maleimide linker, Z = eg1= Ethylene glycol moeity
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa PAO1
64 μg/mL
MIC
PMID30807888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30807888/
RECORD: Rec_0255730 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2; ornithine at 22; non-canonical residue code at 23; non-canonical residue code at 24; peptide is the all-L and all-D form, respectively, lower case letters denote D form. suffix m = conjugate containing a control PNA with two mismatched (interchanged) nucleobases, X = 6-aminohexanoic acid = H2N-(CH2)5COOH residue, Anti-acpP: B= PNA2301 = H-CTCATACTCT-NH2, Mismatch: J = PNA3961 = H-CTCTTACACT-NH2, O = Mal= polar maleimide linker, Z = eg1= Ethylene glycol moeity
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
32 μg/mL
MIC
PMID30807888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30807888/
RECORD: Rec_0276992 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2; ornithine at 22; non-canonical residue code at 23; non-canonical residue code at 24; peptide is the all-L and all-D form, respectively, lower case letters denote D form. suffix m = conjugate containing a control PNA with two mismatched (interchanged) nucleobases, X = 6-aminohexanoic acid = H2N-(CH2)5COOH residue, Anti-acpP: B= PNA2301 = H-CTCATACTCT-NH2, Mismatch: J = PNA3961 = H-CTCTTACACT-NH2, O = Mal= polar maleimide linker, Z = eg1= Ethylene glycol moeity
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae NMI 2697/14
64 μg/mL
MIC
PMID30807888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30807888/
RECORD: Rec_0328948 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 2; ornithine at 22; non-canonical residue code at 23; non-canonical residue code at 24; peptide is the all-L and all-D form, respectively, lower case letters denote D form. suffix m = conjugate containing a control PNA with two mismatched (interchanged) nucleobases, X = 6-aminohexanoic acid = H2N-(CH2)5COOH residue, Anti-acpP: B= PNA2301 = H-CTCATACTCT-NH2, Mismatch: J = PNA3961 = H-CTCTTACACT-NH2, O = Mal= polar maleimide linker, Z = eg1= Ethylene glycol moeity
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae ATCC 13883
8-16 μg/mL
MIC
PMID30807888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30807888/
RECORD: Rec_0408985 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 2; ornithine at 22; non-canonical residue code at 23; non-canonical residue code at 24; peptide is the all-L and all-D form, respectively, lower case letters denote D form. suffix m = conjugate containing a control PNA with two mismatched (interchanged) nucleobases, X = 6-aminohexanoic acid = H2N-(CH2)5COOH residue, Anti-acpP: B= PNA2301 = H-CTCATACTCT-NH2, Mismatch: J = PNA3961 = H-CTCTTACACT-NH2, O = Mal= polar maleimide linker, Z = eg1= Ethylene glycol moeity
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli NMI 3898/15
64
MIC
PMID30807888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30807888/
FIRST PREV 1 2 3
Showing 5 records on this page · Page 3 of 3