Peptide Database

Peptide NameVejovine (Non-disulfide-bridged peptide 2.7) (NDBP-2.7)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length82 amino acids

Chemical FormulaC397H633N101O120S4

DescriptionStandard

        MNAKTLFVVFLIGMLVTEQVEAGIWSSIKNLASKAWNSDIGQSLRNKAAGAINKFVADKIGVTPSQAASMTLDEIVDAMYYD
    

Molecular Weight8869.14 Da

Isoelectric Point (pI)5.18

Net Charge (pH 7.0)-1.49

Net Charge (pH 7.4) -1.73

Charge Density (pH 7.0) -0.0182

GRAVY Index0.23

Hydrophobic Moment 0.56

Boman Index0.18

Instability Index35.32

Aliphatic Index 100.00

Aromaticity 0.0854

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3567.34

LogP -33.53

H-bond Donors 122.0

H-bond Acceptors 123.0

Rotatable Bonds 298.0

Heavy Atoms 622.0

Ring Count 10.0

Amide Bonds 89.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0123701 VERIFIED: YES

Provenance & Taxonomy

OrganismVaejovis mexicanus [Animal]

FamilyNDBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Cytolytic Hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0170698 VERIFIED: YES