Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length118 amino acids

Chemical FormulaC602H941N163O163S6

DescriptionStandard

        PMTPPVAHEPMLLLAVTEFVANSAAFTYFAAGALRKNISSDMLPRRFPLQLRTQSMEVFSPQLQERYPDQPMELHLWARRQPLLSCRPDAVHGTLFSSAEAFVVLPNATRVPAFLLNI
    

Molecular Weight13262.30 Da

Isoelectric Point (pI)8.58

Net Charge (pH 7.0)1.23

Net Charge (pH 7.4) 0.99

Charge Density (pH 7.0) 0.0104

GRAVY Index0.06

Hydrophobic Moment 0.57

Boman Index0.10

Instability Index66.48

Aliphatic Index 91.02

Aromaticity 0.0932

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5123.78

LogP -43.18

H-bond Donors 175.0

H-bond Acceptors 173.0

Rotatable Bonds 415.0

Heavy Atoms 934.0

Ring Count 28.0

Amide Bonds 127.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0166319 VERIFIED: NO

Provenance & Taxonomy

OrganismIrena cyanogastra [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria