Peptide Database

Peptide NameFGF-6

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length171 amino acids

Chemical FormulaC846H1337N243O246S4

DescriptionStandard

        SPAGTRANNTLLDSRGWGTLLSRSRAGLAGEIAGVNWESGYLVGIKRQRRLYCNVGIGFHLQVLPDGRISGTHEENPYSLLEISTVERGVVSLFGVRSALFVAMNSKGRLYATPSFQEECKFRETLLPNNYNAYESDLYQGTYIALSKYGRVKRGSKVSPIMTVTHFLPRI
    

Molecular Weight18976.41 Da

Isoelectric Point (pI)9.73

Net Charge (pH 7.0)7.72

Net Charge (pH 7.4) 7.29

Charge Density (pH 7.0) 0.0451

GRAVY Index-0.24

Hydrophobic Moment 0.60

Boman Index0.00

Instability Index41.21

Aliphatic Index 87.78

Aromaticity 0.0994

Extinction Coeff. Reduced 24410.00

Extinction Coeff. Oxidized 24535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7904.15

LogP -85.05

H-bond Donors 284.0

H-bond Acceptors 261.0

Rotatable Bonds 624.0

Heavy Atoms 1339.0

Ring Count 29.0

Amide Bonds 183.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0052606 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsPredicted N-linked glycosylation of asparagine residue at position 8; predicted disulphide bond formation between cysteine resdiues at positions 53 and 120

Bio-Activity Profile

Function

Immunomodulatory Signaling peptide

Targetfibroblast growth factor receptor 1 (Human); fibroblast growth factor receptor 2 (Human); fibroblast growth factor receptor 4 (Human)