Peptide Database

Peptide Namealpha-II (p62-p72; E65 and E72)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC60H87N13O19

DescriptionStandard

        PQPELPYPQPE
    

Molecular Weight1294.41 Da

Isoelectric Point (pI)4.24

Net Charge (pH 7.0)-2.03

Net Charge (pH 7.4) -2.10

Charge Density (pH 7.0) -0.1847

GRAVY Index-1.77

Hydrophobic Moment 0.02

Boman Index-0.11

Instability Index139.45

Aliphatic Index 35.45

Aromaticity 0.0909

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 486.18

LogP -3.05

H-bond Donors 13.0

H-bond Acceptors 17.0

Rotatable Bonds 33.0

Heavy Atoms 92.0

Ring Count 6.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0199124 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E65; Reported substitutions/positions: E72

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodIntestinal T-cell assay