Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC358H562N98O92S8

DescriptionStandard

        MTQLLLFIVALLVLGHVPPGRSEFKRCWKGQGACRNYCTRQEAYMHLCPDASLCCLPYTLKPPPRPKGEY
    

Molecular Weight7967.41 Da

Isoelectric Point (pI)9.05

Net Charge (pH 7.0)4.62

Net Charge (pH 7.4) 4.19

Charge Density (pH 7.0) 0.0660

GRAVY Index-0.15

Hydrophobic Moment 0.55

Boman Index0.03

Instability Index66.38

Aliphatic Index 79.43

Aromaticity 0.1000

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2991.26

LogP -22.67

H-bond Donors 108.0

H-bond Acceptors 107.0

Rotatable Bonds 249.0

Heavy Atoms 556.0

Ring Count 18.0

Amide Bonds 73.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0250955 VERIFIED: NO

Provenance & Taxonomy

OrganismLoxodonta africana [Animal]

FamilyDefensin

Tax ID9785

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence