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MYP_166447
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Basic Information
Pisum sativum defensin 2 (Psd2; Plant defensin)
Antimicrobial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
47 amino acids
C219H346N76O69S8
Standard
Sequence
KTCENLSGTFKGPCIPDGNCNKHCRNNEHLLSGRCRDDFRCWCTNRC
Physicochemical Analysis
5404.08 Da
8.52
2.86
2.43
0.0609
-1.00
0.47
-0.32
12.59
33.19
0.0638
5500.00
6000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2391.24
-32.76
91.0
82.0
178.0
372.0
8.0
52.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0075410 VERIFIED: YES
Provenance & Taxonomy
Pisum sativum [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Aspergillus versicolor
0.34 μg/mL
MIC
PMID10860545;30639288 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10860545/
RECORD: Rec_0079855 VERIFIED: YES
Provenance & Taxonomy
Pisum sativum [Plant]
Defensin
3888
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antifungal
Saccharomyces cerevisiae
100 μg/mL
IC50
PaperPubMed PMID 10860545 PMID10860545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10860545/
RECORD: Rec_0159740 VERIFIED: YES
Provenance & Taxonomy
Pisum sativum [Plant]
Defensin
3888
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antifungal
Fusarium solani
8.5 μg/mL
IC50
PaperPubMed PMID 10860545 PMID10860545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10860545/
RECORD: Rec_0160239 VERIFIED: YES
Provenance & Taxonomy
Pisum sativum [Plant]
Defensin
3888
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antifungal
Fusarium moniliforme
10 μg/mL
IC50
PaperPubMed PMID 10860545 PMID10860545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10860545/
RECORD: Rec_0160844 VERIFIED: YES
Provenance & Taxonomy
Pisum sativum [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
3-47, 14-35, 20-41, 24-43
Bio-Activity Profile
Antimicrobial Antifungal
NOTE: PD+ = potato dextrose medium supplemented with 1 mM CaCl2
PMID10860545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10860545/
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